About Us


The DHA/EPA Omega-3 Institute was founded to help educate health professionals and the public about the physiologically-essential nutrients - docosahexaenoic acid (DHA), and eicosapentaenoic acid (EPA). These types of omega-3 fatty acids are most commonly found in fish, seafood, and other marine sources.

Dr. Bruce Holub Bio:

Dr. Holub is University Professor Emeritus, Department of Human Health & Nutritional Sciences at the University of Guelph. He received his B.Sc. degree from the University of Guelph (1967) and his Ph.D. (Major in Biochemistry with Minor in Nutrition) from the University of Toronto (1971). Dr. Holub received Post-doctoral training as an MRC Fellow at the University of Michigan Medical School. He has served as President, Nutrition Society of Canada and Chair, Nutrition Task Force (Heart & Stroke Foundation of Ontario). He has authored over 200 papers in scientific journals (medical, nutrition, other) in addition to various book chapters and conference proceedings. His research program is focused on dietary omega-3 fatty acids from fish/fish oils, plant oils, and resulting nutraceuticals plus functional foods for human health and the prevention/management of cardiovascular disease and other chronic disorders.

As well, he has been active in the evaluation of nutraceuticals and agri-foods for improving human health, disease prevention and management, and their potential for considerable cost-savings to the healthcare system. He has also been studying the composition and health risks associated with foods containing 'trans' fatty acids. Dr. Holub also maintains active collaborative research with clinical groups at various Canadian medical schools, the Mayo Clinic in the United States, Japan, Greenland, and the agri-food sectors.

Dr. Holub has spoken at over 300 off-campus events (invited speaker-to universities, international conferences, food companies, medical groups, government agencies, lay groups) in over 15 countries. Dr. Holub has over 30 appearances on national TV in Canada (national news on CBC, CTV, Global, in addition to talk shows including 'Marketplace', 'Michael Coren Live', '2nd Opinion', 'Medical Hotseat', and others). Dr. Holub has given over 200 interviews for various newspapers in Canada and the U.S. (Globe and Mail, Toronto Star, National Post, Montreal Gazette, Hamilton Spectator, etc) and magazines (Men's Health, Prevention Magazine, Chatelaine, McLean 's, etc).

Recent selected publications:


Ramadeen, A., Laurent, G., DosSantos, C., Hu, X., Connelly, K., Holub, B., Mangat, I. and Dorian, P.  N-3 polyunsaturated fatty acids alter gene expression profile and reduce vulnerability to atrial fibrillation in a dog model of cardiomyopathy. Heart Rhythm., 7 (4): 520-528, 2010. 

Holub, B., Piekarski, J., Rowe, W. and Wlodek, M.  Correlation of omega-3 levels in serum phospholipid from 2053 human blood samples with key fatty acid ratios. Nutrition Journal, 8: 58-64, 2009. 

Holub, B.J., Docosahexaenoic acid (DHA) and cardiovascular risk factors. Prostaglandins Leukot Essent Fatty Acids, 81(2-3):199-204, 2009. 

Barrow, C.J., Nolan C., and Holub B.J.  Bioequivalence of encapsulated and microencapsulated fish-oil supplementation. Journal of Functional Foods, 1:38-43, 2009.

Madden, S.M.M., Garrioch, C.F., and Holub, B.J.  Direct diet quantification indicates low intakes of (n-3) fatty acids in children 4 to 8 years old. J. Nutr., 139: 1-5, 2009. 

Laurent, G., Moe, G., Hu, X., Holub, B., Leong-Poi, H., Trogadis, J., Connelly, K., Courtman, D., Strauss, B. H., and Dorian, P.  Long chain n-3 polyunsaturated fatty acids reduce atrial vulnerability in a novel canine pacing model. Cardiovasc. Res., 77(1):89-97, 2008. 

Lucas, M., Dewailly, E., Blanchet, C., Gingras, S., and Holub, B.J.  Plasma omega-3 and psychological distress among Nunavik Inuit (Canada). Psychiatry Res., 167:266-78, 2009. Holub, B. J. Treating hypertriglyceridemia. Can. Medical Assoc. J., 177(6): 604, 2007. 

Rose, EL. and B.J. Holub.  Effects of a liquid egg product containing fish oil on selected cardiovascular disease risk factors: A randomized crossover trial. Food. Res. Int., 39: 910-916, 2006.

DHA/EPA Omega-3 Institute Team:


Dr. Bruce Holub, PhD Scientific Director
Steve Holub, M.A. Managing Director
Laura Holub, M.Sc.
Research Associate


Contact Information:

If you would like to ask Dr. Holub an omega-3 related health question, please use this form to reach him.  Alternatively, if you would like to contact the DHA/EPA Omega-3 Institute for business related matters, please use this contact form.  We can also be reached via standard mail at the following address:

DHA/EPA Omega-3 Institute
150 Research Lane, Rm. 100
University of Guelph Research Park
Guelph, ON , Canada N1G 4T2